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Thus, unless there is evidence of excessive and overly prolonged inflammation unlikely in otherwise healthy, injured athletes caution is warranted regarding interventions aimed at eliminating inflammation

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Dees EC, Aftimos PG, Van Oordt H, De Vries EGE, Neven P, Pegram MD, et al

showed that prostaglandin E2 (PGE2) suppresses the expression of the IL-2 receptor gamma chain and mitochondrial function, thereby disrupting the expansion of T cells in the TME

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