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Description
Mitochondrial quality control Excess lipids in hepatocytes stimulate the production of both mitochondrial ROS production and FA oxidation

Beta-carotene supplementation has been linked with lung cancer in smokers, vitamin E with prostate cancer, and vitamin A with a higher risk of dying [17, 18]
Insulin and adrenergic receptor signaling: crosstalk in heart

The development of small molecule inhibitors of MBOAT1 and MBOAT2, along with the upstream enzyme ACSL3, could allow for the development of potent new drug combinations targeting lipid metabolism to modulate ferroptosis for therapeutic benefit

See Supplementary (SF1) for the representativeness of the sample

This effect is related to direct immunosuppression in the tumor microenvironment, contributing to cancer growth and progression [42]
