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Specifically, one RD each from two neighbouring CBS dimers interact in a butterfly-like dimeric arrangement, related by C2 symmetry, such that the loop 516525 from an RD of one dimer forms a clasp around an RD of the neighbouring dimer

Using a batch of hops that are rich in free thiols, cold-side additions can lead to appreciable levels, ranging from 0.1 - 0.3 g/L

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VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400

HK-2 cells are derived from human renal tubular epithelial cells, terminal cells for uric acid production and excretion