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doi: 10.3390/antiox12091732 164 ReisJGorgullaCMassariMMarcheseSValenteSNoceBet al

Chronic inflammation and disturbances in brain neurotrophic signaling, particularly involving brain-derived neurotrophic factor (BDNF), are thought to be major contributors to this link between CRC and depression (79)

doi: 10.1128/IAI.01984-06

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Furthermore, NO plays a significant role in hemostasis by balancing clot formation and dissolution, promoting fibrinolysisthe process that breaks down clotsthereby preventing excessive clotting that could lead to vascular occlusion (Naseem, 2005)

Redox signaling and the emerging therapeutic potential of thiol antioxidants