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Clin Res Hepatol Gastroenterol

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Fibromyalgia syndrome pathology andenvironmental influences on afflictions with medically unexplained symptoms

Mutations identified in patients with defective lipoic acid metabolism affect genes involved in the synthesis of iron-sulfur clusters and genes coding for lipoic acid synthetase ( LIAS ), lipoyl transferase 1 ( LIPT1 ), and dihydrolipoamide dehydrogenase (E3 component of -ketoacid dehydrogenase complexes

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