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Amino acid starvation results in reduced synthesis of myelin components Cuprizone consumption may alternatively induce demyelination by reducing myelin protein and lipid synthesis which destabilizes the myelin sheath
2020;8:e2843
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167 , 168 Currently, CD38 antibodies are also combined with PIs such as carfilzomib and bortezomib, however the exact mechanisms by which these combinations exert their efficacy are less clear than combinations with IMiDs
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