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Several studies have shown that S1P plays a crucial role in tissue fibrosis [21] regulating different aspects, including the permeability of the vascular barrier, the recruitment of inflammatory cells, and the proliferation and differentiation of myofibroblasts, through the transactivation of the TGF- signalling pathway [22]

GalNAc-lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy

Beverly Ann Tappen Guilloz 49 Beverly Ann Tappen Guilloz 49, December 25, 2004