hepatocyte glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease Glutathione in liver diseases and

[DOI] [PubMed] [Google Scholar] 273.Sghaier D.B., Pedro S., Diniz M.S., Duarte B., Caador I., Sleimi N

found that immunotherapy, in synergy with the FSP1 inhibitor iFSP1, was able to significantly increase DC, macrophage, and T cell immune infiltration, and inhibit HCC progression

The procedure involves mixing the DTNB Reagent with sample, removing protein precipitates for proteinaceous samples, adding a second Reagent and reading the optical density

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J Steroid Biochem Mol Biol 1998

This indicates the existence of a GGCT-mediated Gln metabolic shunt in tumor cells: Gln is prioritized for conversion to GSH, which scavenges ROS, alleviates oxidative stress, and ultimately promotes tumor cell proliferation