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When the function of mitochondria declines, the ability to remove reactive oxygen species (ROS) decreases, resulting in a decrease of mitochondrial membrane potential (MMP) and DNA copy number of mitochondria (mtDNA copy number) mutations, thus causing cell apoptosis [13, 14]

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It is a lipid repair enzyme that functions to detoxify lipid hydroperoxides, which are harmful reactive oxygen species (ROS) generated during oxidative stress