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Ruf S, Rajagopal S, Kadnur SV, Hallur MS, Rani S, Kristam R, Swaminathan S, Zope BR, Gondrala PK, Swamy I (2022) Novel tricyclic small molecule inhibitors of Nicotinamide N -methyltransferase for the treatment of metabolic disorders

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Closing Perspective on 5Amino1MQ 5-Amino-1MQ represents a shift in metabolic research from hormonal manipulation to cellular optimization. By targeting the NNMT enzyme, it addresses a fundamental inefficiency in the metabolism of obese and aged cells

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