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Description
When Melanotan II activates MC1R , it triggers intracellular signaling (commonly described via the cAMP pathway ) that upregulates melanin-related processes in melanocytes, increasing melanin production and shifting pigmentation expression over time

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stock solution 40 mM in ethanol), membranes were incubated in 1 ml of 50 mM TrisHCl, pH 8.0 for 20 min at 37C prior to measurement (DeckersHebestreit & Altendorf, 1992)
