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doi: 10.1053/j.ajkd.2008.08.022 12 SrikanthVSinclairAJHill-BriggsFMoranCBiesselsGJ

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Shaking looks faster, but it forces the air above the powder into the liquid as foam, and you have to wait for that foam to settle before you can draw so it doesnt save time

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[5] In summary, pyridoxine may decrease the efficacy of certain medications (notably levodopa and some anticonvulsants), and various drugs can in turn precipitate vitamin B deficiency