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For most men over 40, its a HORMONAL problem

However, without concrete evidence, the theory was largely forgottenuntil now

71 Interestingly, metabolite profiling of cells treated with Cu ionophore presents a time-dependent increase in the dysregulation of many TCA cycle-associated metabolites, and inhibiting the electron transport chain complexes I and II significantly reduced Cu-induced cell death

Philos Trans R Soc B Biol Sci 355:14771488

It also plays a role in glutathione synthesis, which supports detoxification pathways

By promoting cellular repair and reducing inflammatory markers in laboratory models, it provides a platform for studying regenerative medicine techniques relevant to sports science