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Kong et al., 2017)

Conversely, Bdh1 overexpression successfully attenuated lipotoxicity, oxidative stress-induced hepatic injury, inflammation and apoptosis in the fatty liver from db/db mice (Xu et al., 2022)

Accessed 12/3/20, VeDA

This defect was linked to impaired brown adipose tissue thermogenesis, 6 as reflected by reduced mitochondrial respiration and decreased circulating long-chain acylcarnitines (Fig

Carnitine serves a second critical metabolic function, buffering the Coenzyme A pool against accumulation of short chain acetyl-CoAs, which at increasing levels reduce the activity of the pyuvate dehydrogenase complex (PDC)
