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The intermittent treatment design follows preclinical evidence that demonstrated senescent cells require 2-4 weeks to develop and complete senescent cell clearance is not required for disease modifying effects

, 65 , 1662-1684, Li, J., Sun, C., Cai, W., Li, J., Rosen, B
At 2mL in a 10mg vial, a 2.5mg starting dose is exactly 50 units and a 5mg dose is exactly 100 units -- no awkward fractions
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To view a copy of this licence, visit About this article Cite this article Guo, X., Kong, L., Wen, Y

[DOI] [PubMed] [Google Scholar] Jakoby W.B., Stevens J.L., Duffel M.W., Weisiger R.A
