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elegans, Drosophila, and mammals
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The rate of de novo synthesis is responsive to environmental factors
doi: 10.1111/bph.14645
Reduced FKBP5 methylation results in the upregulation of FKBP51 protein expression, which positively correlates with the expression of numerous pro-inflammatory genes, consequently increasing the granulocyte/lymphocyte ratio and IL-8 levels, thus driving peripheral inflammation (365)
