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IdeguchiHOhnoSTakaseKHattoriHKirinoYTakenoMet al

This interaction is mediated by dual binding, with FHD mainly binding to the p53 TAD and FOXO4 CR3 binding to the p53 DNA-binding domain (DBD) 38 (Figure

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19 In light of the potential for adverse drug interactions, oral health professionals should carefully review patients use of herbal supplements and examine potential conflicts with prescription and OTC medications, especially when prescribed in the dental office

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