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10.1152/ajpregu.00498.2012

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Mass spectrometric analysis was performed using a QTRAP 5000 triple quadrupole mass spectrometer equipped with an electrospray ionization (ESI) source (Applied Biosystems, USA)

Tight junction structures are made up of various elements, including transmembrane proteins (claudins, occludin, and tricellulin), tight junction-associated proteins (junctional adhesion molecules 13), and intracellular scaffold proteins (zonula occludens 13), and regulate paracellular passage of molecules based on charge and size selectivity under homeostatic conditions (10)

Ethics statement The studies involving humans were approved by Ethics Committee for Clinical Research of La Paz University Hospital (Ref

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