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But they came from a single research group, conducted in a single country, with limited independent replication a well-documented limitation in this literature

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(2012) published that miR-133b reduces GSTP1 expression by 2.1 fold in prostate cancer cells

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Impaired cell signaling pathways also disrupt this cycle, and once this happens, pigment can no longer be regenerated, leading to permanent greying

This bypasses first-pass metabolism in the liver, potentially increasing bioavailability