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Our observations of a concentration-dependent inhibition of NFT-dependent glutathione synthesis stimulation (Fig
Books (edited and written) Walker AR, et al
Not only that, the IDoi@TBC-Hf nanoparticles formed by loading the IDO inhibitor (IDoi) indoleamine 2,3-dioxygenase into TBC-Hf (a new nMOF) using the highly porous structure of the nanometal-organic framework (nMOF) can reverse the inhibitory tumor microenvironment by releasing IDoi after local injection, and combined with PDT can induce ICD and further stimulate the immune system, leading to infiltration of CD4 + T and CD8 + T cells in the TME and effectively controlling both local and distant tumors (188)
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Animal studies show improved tensile strength, faster collagen formation, and better biomechanical outcomes in torn tendons and ligaments
Oncogene 16 , 19731979 (1998)
