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Use of MSC-derived small extracellular vesicles (MSC-SEVs) is a novel strategy for the treatment of IDD

A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis

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doi: 10.3389/fendo.2022.891297 49 ChangZPDengGFShaoYYXuDZhaoYNSunYFet al

Its conceivable that this close symbiotic alliance between fungi and plants is also a key mechanism for the incorporation of ergothioneine into the plant system

Its cytotoxic mode of action is mediated by its interaction with DNA to form DNA adducts, primarily intrastrand crosslink adducts, which activate several signal transduction pathways, including those involving ATR, p53, p73, and MAPK, and culminate in the activation of apoptosis