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cells were fixed (4% paraformaldehyde), permeabilized (0.5% Triton X-100), and labeled with secondary AlexaFluor 488 goat- -human IgG Ab (Biosource), with 2 cold PBS washing in between steps

Abbreviations CT: computed tomography ROS: reactive oxygen species SSBs: single stranded breaks DSBs: double stranded breaks H2AX: gamma-H2AX foci NAC: N -acetylcysteine PlmtVC: 6- O -palmitoylascorbate l-AA: l-ascorbic acid CVC: carvacrol sEg: sinapoyl-E-glucoside q3Or7Og: quercetin-3- O -rhamnoside-7-O-glucoside q3Or: quercetin-3- O -rhamnoside l7O2ag: luteolin-7- O -(2-apiosyl)-glucoside DNC: dendrosomal nanoformulation of curcumin DA: dendrodoine analog EGCg: epigallocatechin-3-gallate HO1: oxygenase 1 IF: isofraxidin mESC: mouse embryonic stem cells CAPE: caffeic acid phenethyl ester GHS: glutathione GSSG: oxidized glutathione TA: -tocopherol acetate AA: ascorbic acid References Ozasa K, Shimizu Y, Suyama A, Kasagi F, Soda M, et al

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Role of NLRP3 inflammasome and oxidative stress in hepatic insulin resistance and the ameliorative effect of phytochemical intervention

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