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In addition, small molecule inhibitors including SLC7A11 inhibitor HG106 and GCLC inhibitor buthionine sulfoximine (BSO) were introduced to investigate their effects on ROS, GSH levels and cellular viability in VRK2-KO and VRK2-KD cells, and the results were consistent with the above knockdown experiment (Fig

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aminopropylation SAMe is decarboxylated to produce polyamines which promote DNA and protein synthesis, necessary for normal hepatocyte growth and repair

Conversely, other research confirms that mesenchymal stem cells (MSCs) EVs are internalized by microglia and astrocytes