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Recent proteomic and metabolomic studies have identified specific microbial signatures associated with the disease, notably a severe depletion of butyrate-producing bacteria like Faecalibacterium prausnitzii

Biochemical analyses further revealed enhanced cognitive performance and a notable reduction in free radical production, indicating mitigation of oxidative stress

Taxonomic classification was assigned in the QIIME2 pipeline using the classify-sklearn algorithm under feature-classifier plugin against a pretrained classifier based on the Greengenes2 2024.9 release (McDonald et al

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135,136,137 Moreover, Badgley et al

Cells were then incubated with HBSS containing 2 M C11-BODIPY 581/591 (Invitrogen D-3861) at 37 C for 30 min in dark