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They directly stimulate tissue remodeling and matrix deposition through the secretion of mediators such as SPP1 and TGF-1 ( With the onset of malignant transformation, the functional axis of these pre-existing macrophage subpopulations undergoes a decisive shift toward strong immunosuppression

Food Meas

Cyanocobalamin is a synthetic, stable form widely used in supplements and fortified foods, whilst methylcobalamin is a naturally occurring, bioactive form found in animal products

Crit Rev Food Sci Nutr 64(27):97719788

Wright SS, Kumari P, Fraile-greda V, Wang C, Shivcharan S, Kappelhoff S, et al

Intake of nutrient and non-nutrient dietary antioxidants: Contribution of macromolecular antioxidant polyphenols in an elderly Mediterranean population