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The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates

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When the Cosmetic Ingredient Review (CIR) Expert Panel went back through that study, they found methodological flaws and decided the results couldn't be interpreted as proof of extra risk

Separation of selenium ions protects yeast cells against their toxic effects

The embryonic life stage could supplement enough to cover these deficiencies because an embryo is the simplest multicellular individual developed from a single cell, which not only complies with the 3R principles but also could allow a convenient study of its toxic effects from cell/tissue level to the ontogenetic level
