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Effective platelet inhibition requires 95% COX-1 blockade, yet studies show that 24 h after morning intake, a quarter of cardiovascular patients have insufficient inhibition

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1,4 To decrease the likelihood of misinterpretation, pharmacists can help by identifying medications at high risk for causing false-negatives and false-positives and choosing medications less likely to cause these inaccuracies

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In addition, for therapeutic application, it is preferable that an enzyme should have both structural and functional stabilities under severe conditions
