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Description
Oncoimmunology (2013) 2:e27127

Because glutamine is the source of -KG, glutaminase inhibitors such as BPTES interfere with -KG homeostasis and lead to inhibited proliferation in cancer cells carrying this mutant IDH1 (Seltzer et al., 2010)

These peptides can activate or inhibit various enzymes, receptors, and proteins, influencing metabolism, immune responses, and neurotransmitter activity

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Dysbiosis and increased intestinal permeability (leaky gut) may amplify neuroinflammatory state of the brain, further justifying the need for research into interventions combining metabolic and microbiota-based therapies

7) Fighting Infections Viral infections flood the body with oxidative stress due to inflammation, using up more glutathione
