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doi: 10.1007/s00018-006-6010-1 118 LeeRKermaniPTengKKHempsteadBL

Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion

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Treg cells shape the immunosuppressive TME through multiple mechanisms, with their metabolic vulnerabilities (particularly ferroptosis sensitivity) offering a critical breakthrough for reversing tumor immune escape

The Mitochondrial Connection: Glutathione, NAD+, and Ageing Glutathione plays a critical role in mitochondrial health