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Hormone and Metabolic Modulators added to the Prohibited List, including elacestrant (added as an anti-estrogen), S519 and S597 (examples of insulin-mimetics), and MOTSc (an example of an AMP-activated protein kinase activator)

47,48 Age-related degenerative changes make older adults more susceptible to nerve damage, with DN prevalence significantly increasing in individuals over 50 years old

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It can significantly promote the synthesis and release of growth hormone (GH) from cells in the pituitary gland, improving the serum concentrations of GH and subsequently insulin-like growth factor 1 (IGF-1) in animals and humans

Since the body cannot produce B12 naturally, supplementation is often essential, particularly for individuals with dietary restrictions or those who have trouble absorbing nutrients

Vitamin B6 is essential for the synthesis of neurotransmitters and the transformation of food into energy