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The results pointed out that metformin treatment for more than 4 years can significantly reduce the risk of PD (HR 0.19, 95% CI 0.120.31) [155]

This is not a true detoxification process as the dihydrodiol product can rearrange at neutral pH values to form a dialdehydic phenolate ion

doi: 10.3389/fnins.2019.00545 50

We then examined whether sampling source, sex, age, publication year, latitude, and source of healthy volunteers were variables that could affect the meta-analysis outcome

Comparative studies involving repair-associated peptides in preclinical models