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demonstrated that SalB effectively blocked the hypertrophic response in neonatal rat cardiomyocytes exposed to angiotensin II ( + depletion in cells ( 4.5 Diabetic cardiomyopathy (DCM) DCM, a condition commonly associated with diabetes mellitus, is characterized by structural and functional abnormalities in the myocardium ( 4.6 Septic cardiomyopathy (SCM) SCM is a systemic inflammatory response triggered by infection that impairs heart function ( 4.7 Uremic cardiomyopathy (UC) UC, a heart disease associated with renal failure, is often characterized by myocardial fibrosis, declining cardiac function, and elevated oxidative stress ( 4.8 Doxorubicin-induced cardiomyopathy (DIC) Doxorubicin (DOX), a widely used chemotherapeutic agent, is known for its cardiotoxicity, which induces oxidative stress, inflammation, and ER stress in cardiomyocytes, ultimately leading to cardiomyocyte apoptosis and heart injury ( 4.9 Cisplatin-induced cardiac injury Cisplatin, a widely used chemotherapeutic agent, is commonly linked to severe cardiotoxicity and oxidative stress, resulting in cardiac dysfunction ( 5 Research on the compatibility and dosage forms of SalB To overcome the limitations of SalB, numerous strategies, including drug compatibility and dosage form modifications, have been explored

However, an overview of the basics of the regulation of induction of autophagy and the major protein activities of (macro)autophagy will be carried out

Research studies have shown that anthocyanins can neutralize ROS in cells, inhibit the generation of oxidative stress in nerve cells and simultaneously reduce the level of intracellular oxidative stress by effectively activating the production of endogenous antioxidant enzymes 176