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GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects

With a view to identifying more medicinal natural products and their synthetic variations, it is ideal to take a deep look into ethnomedicine, for example, traditional Chinese medicine (TCM)

Miller DR
However, current evidence suggests this is more likely due to hormonal shifts caused by rapid weight loss rather than a direct effect of the medicine itself

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The loss of PLC2 results in the loss of phosphorylation of Pyk-2, ERK, and, surprisingly, SFK activity following poly-RGD stimulation (Cremasco et al., 2008)
