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As a key mitokine, MOTS-c is at the center of research into anti-aging interventions

Standardization of Senescence Biomarkers: A major challenge in both the development and application of senescence-targeting therapies is the identification of reliable biomarkers that can accurately assess the presence of senescent cells and their effects.256 Current biomarkers for senescence, such as p16^INK4a, -galactosidase activity, and SASP factors, are useful in research settings, but their clinical applicability remains limited

If 2 mg feels rough: Some users start lower at 1 mg per week for the first 4 weeks

Ciez, R

It is especially beneficial for older adults, pregnant women, and those at higher risk of severe illness

J Pharm Innov 18 , 965979 (2023)