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Nat Immunol (2015) 16(4):34353.10.1038/ni.3123 11 PachecoARBarileDUnderwoodMAMillsDA

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Lipid-based nanoparticles: application and recent advances in cancer treatment

This research highlights that all three doses of FD (50 mg/kg, 100 mg/kg and 200 mg/kg) effectively improved spatial learning and memory in D-gal and AlCl 3 -induced AD rats, as evidenced by the mEPM test

ASTs ability to ROS and modulate gene expression related to oxidative stress offers neuroprotective effects against neurodegenerative diseases such as AD and PD

However, caution should be exercised when using CBD concurrently with drugs that influence cardiac repolarization or impair drug metabolism, as well as in certain pathophysiological situations, such as hypokalemia, channelopathies, diabetes mellitus, hypertrophic myocardiopathy, or heart failure, among others, CBD can have an additive effect, further increasing the proarrhythmic risk and the possible incidence of sudden cardiac death (Figure 5)