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Extremely low prevalence of amyloid positron emission tomography positivity in Parkinson's disease without dementia

2022TQ0249), the Fundamental Research Funds for the Central Universities (Nos
Yale medical Center

Treatment strategies aiming to interfere with the formation of amyloid (A) plaques and neurofibrillary tangles (NFTs), the two major AD hallmarks, have shown modest or no effect
In addition, the complexes can be reduced to their active platinum(II) species in the reductive/hypoxic environment of the malignant tissue, leading to a more tumor-specific activation

Nat Chem Biol 13:9198 Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M et al (2015) Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death