what can deplete glutathione Role of GSH in apoptosis and cytotoxicity . depletion is an... Controlling glutathione entry into mitochondria:

Activation of this pathway sets off a protective cascade of production of powerful antioxidants such as glutathione, superoxide dismutase (SOD) and catalase

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Altered glutathione (GSH, an important antioxidant and neuromodulator) and gamma-aminobutyric acid (GABA, a major inhibitory neurotransmitter) levels have been proposed as potential contributors to the biology underlying ASD

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