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Localization of CYP2E1 to mitochondria enhances the local production of HER and ROS, particularly in hepatocytes, contributing to impaired mitochondrial integrity and function [34,35]

Key trials like STEP, SURPASS, and SELECT have demonstrated their efficacy in glycemic control (HbA1c reductions of 1.02.0%) [1, 3, 4], weight loss (1020% mean body weight reduction) [2, 3, 4], and cardiovascular risk reduction [4, 7]

Soghomonian and Martin, 1998

The pituitary gland is, in turn, controlled by the hypothalamus

Finally, B12 is required to make myelin, the protective layer that coats nerve cells. B12 also works alongside folate to produce red blood cells, and without adequate B12 those cells grow abnormally large and lose their ability to carry oxygen efficiently

These qualities, combined with their ability to reduce inflammation and encourage tissue repair, make exosomes particularly promising for maternal health and postpartum recovery