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Moreover, data from post-marketing surveillance and large population-based studies, especially from the US, are limited

Mode of administration of dulaglutide: implications for treatment adherence

& Patrick, J

Furthermore, the tolerability of GLP-1 RA is often dose-limiting

What actually happens is the GLP-1 agonist starts slowing gastric emptying while a large bolus of food is entering the stomach
This can affect potency and effectiveness
