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This has serious consequences: not merely for the individuals afflicted with the condition, but for healthcare systems more generally as it can result in an array of comorbidities

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As in Fig (4) the hydroxylation of AFB1 at C4 or C22 produces, AFM1 and AFQ1, respectively

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This complexity has taken to many groups to investigate this exciting topic using metabolomics, given that the circulating metabolome provides a snapshot of the physiological state of the organism 1,2

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However, the effects of IGF1 were evaluated in combination with basic fibroblast growth factor and an interleukin-1 receptor antagonist, making it challenging to discern the specific impact of IGF1 in the disease 41

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