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This aligns with previous evidence linking insulin resistance and obesity with impaired testosterone production [14], implying that the metabolic improvements induced by GLP-1 therapy may restore androgen levels

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Metabolomics data are available on the public Metabolome Express server (www.metabolome-express.org), with the accession reference 33SCOMPLET

Hepatology 40:221231

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Long term lithium treatment suppresses p 53 and Bax expression but increases Bcl-2 expression