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The pathological characteristics of ALI involve extensive inflammation resulting in harm to alveolar epithelial cells (AECs), breakdown of the pulmonary vascular endothelial barrier and subsequent accumulation of protein-rich inflammatory edema fluid within the alveolar spaces, ultimately causing diffuse alveolar damage (6)

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Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD et al (1994)

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Contamination at any point introduces bacteria that multiply rapidly in the aqueous solution, causing infections at the injection site or systemic inflammatory responses