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Description
Lack of these well-defined molecular targets limits therapeutic efficacy, making TNBC particularly difficult to treat, leading to high tumor heterogeneity, increased metastatic potential, and poor prognosis 2

Truong TH, Carroll KS 2013 Redox regulation of protein kinases

Control and acivicin-treated cells were subjected to 10 g/ml Tunicamycin for 48 h

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

To this end, many drugs have been repurposed, including tocilizumab, sarilumab, heparin, chloroquine, ivermectin, sarilumab, chromones (Sestili and Stocchi, 2020)
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Final thoughts Peptides for dark circles provide targeted intervention addressing specific mechanisms including skin thickening obscuring vessels, melanin inhibition reducing pigmentation, anti-inflammatory effects decreasing puffiness, and circulation enhancement reducing blood pooling
