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Pharmacological inhibitors of cGAS and STING, as well as strategies to neutralize type I interferon signaling, have shown benefits in reducing neuroinflammation and preserving neuronal function in preclinical
These side effects are reversible once stopping the medication
Roco JA, Mesin L, Binder SC, Nefzger C, Gonzalez-Figueroa P, Canete PF, et al
Th1 cells amplify macrophage activation through IFN- (67), enhancing M1 polarization and accelerating glomerulosclerosis
Camacho, Monoclonal antibodies as biotherapeutics, in Biotherapeutics: from small to large molecules and cells
2019;14 doi: 10.1371/journal.pone.0227278
