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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Sun R., Xu D., Wei Q., Zhang B., Aa J., Wang G., Xie Y

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We have chosen prpTDP-43 A315T mice for our analyses, because this mouse model of TDP-43 pathology was generated based on the A315T mutation detected in the TARDP gene of ALS patients, who had TDP-43 pathology in their cortex 19 , and because the mouse model strictly recapitulated many aspects of the disease, including progressive CSMN degeneration 16

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