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Conclusion Long-term HF diet of newborn offspring causes liver steatosis and inhibits the protective effect of UPR induced by ER stress with hepatocyte apoptosis

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IsoalloLCA, a lithocholic acid (LCA) derivative, enhances peripheral Treg (pTreg) differentiation via FoxP3 upregulation in a TGF- and CNS3-dependent manner through mitochondrial Reactive Oxygen Species (ROS), independent of the Vitamin D Receptor (VDR) (70)

It also neutralizes the harmful molecules that are floating in our bodies

For example, the tumor suppressor protein TP53/p53 (tumor protein p53) can inhibit ferroptosis in human colorectal cancer cells by binding to DPP4 (dipeptidyl peptidase 4) [70]

Parent et al., 2015
