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Interestingly, it has been found that this syndrome can also be caused by a mutation in the mitochondrial ribosomal protein MRPS22 with deficiencies of OXPHOS complexes I, III, and IV in fibroblast mitochondria [392]

Metabolomic and inflammatory signatures of symptom dimensions in major depression

For instance, consuming high fiber foods can result in gut bacteria production of short chain fatty acids, such as butyrate and propionate

Filipa G Mateus, Silvia Moreira, Ana D Martins, Pedro F Oliveira, Marco G Alves , Maria de Lourdes Pereira, 2023 Sep 6 -

[26] Carnitine blood levels and muscle stores can become low, which may contribute to anemia, muscle weakness, fatigue, altered levels of blood fats, and heart disorders