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For histone H2b, Epitalon bound at site 3 near the N-terminal alpha helix, formed 12 docking solutions and binding via the sequence Val-Glu-Thr-Ser-Asn-Ser-Asn with an energy of 23.10 kcal/mol

Having a lack of intrinsic factor (IF) , a substance that binds to B12 so it can be absorbed into the bloodstream (5)

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This creates a powerful feeling of fullness that reduces caloric intake
