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Second, normalization to the mitochondrial matrix enzyme citrate synthase (CS), an established marker for mitochondrial content, enabled us to distinguish whether the increase in OXPHOS proteins was due to an overall rise in mitochondrial content or represented a selective upregulation of the OXPHOS complexes on the mitochondrial membrane relative to other mitochondrial proteins

Meanwhile, the mechanism of binding of PKUMDL- LDL-102 has been studied using molecular docking and detected as an hGPX4-C activator [8]

A role for trapping kinetically stable Co(III) ions in the detection of cobalt by CblA is an intriguing possibility

Bletilla striata polysaccharides alleviate metabolic dysfunction-associated steatotic liver disease through enhancing hepatocyte RelA/HNF1 signaling

Recent groundbreaking findings have identified GTPSCS as lactyl-CoA synthetase in the nucleus of glioma cells, promoting glioma progression through P300-mediated histone lactylation [23]

doi: 10.3389/fmolb.2022.976862 Received 23 June 2022 Accepted 26 July 2022 Published 17 August 2022 Volume 9 - 2022 Edited by Junhong Han, Sichuan University, China Reviewed by Minjie Zhang, University of Southern California, United States Aurelien Serandour, Ecole Centrale de Nantes, France Updates Copyright 2022 Turpin and Salbert