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A major limitation for translating NRF2-targeted strategies into clinical practice is the substantial genetic and molecular heterogeneity of HCC, which is due to diverse etiologies and distinct oncogenic alterations
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doi: 10.1111/j.1572-0241.2005.41583.x
In skeletal muscle, IGF-1 LR3 activates satellite cells, promoting their proliferation and differentiation into mature muscle fibersa process termed hyperplasia (increase in cell number) distinct from hypertrophy (increase in cell size)
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